Addressing nutritional shortfalls
DSM welcomes the publication of a letter in the Annals of Internal Medicine today, which argues that daily multivitamin supplementation is a safe and effective way to fortify the diet of individuals to achieve the recommended intake of essential micronutrients. The letter was written in response to a previous communication, which claimed that there is little or no evidence to support the use of vitamin and mineral supplements by the majority of the population in the United States (US).
The response was drafted by a group of scientists led by Dr. Balz Frei, Linus Pauling Institute at Oregon State University. Dr. Frei comments:
The evidence cited in the letter includes the findings of numerous studies to demonstrate that the majority of adults in the US do not get the Estimated Average Requirement of essential micronutrients, including vitamins A, D, E and K, magnesium, calcium and potassium from their diet. The authors also highlight the role that multivitamin and mineral supplements may play in helping to decrease the risk of chronic disease. For example, the Physicians’ Health Study II is the largest and longest randomized clinical trial of a multivitamin and mineral supplement conducted to date and reported a statistically significant 8% reduction in total cancer incidence in male physicians.
Prof. Manfred Eggersdorfer, Senior Vice-President, Nutrition Science & Advocacy at DSM and Professor for Healthy Ageing at the University of Groningen, adds:
 Frei B, Ames BN, Blumberg JB, Willett WC. Enough is enough [Letter]. Ann Intern Med. 2014:160(11):807
 Guallar E, Stranges S, Mulrow C, Appel LJ, Miller ER 3rd. Enough is enough: Stop wasting money on vitamin and mineral supplements [Editorial]. Ann Intern Med. 2013;159:850-1.
 Fulgoni VL 3rd, Keast DR, Bailey RL, Dwyer J. Foods, fortificants, and supplements: Where do Americans get their nutrients? J Nutr. 2011;141:1847-54.
 Gaziano JM, Sesso HD, Christen WG, Bubes V, Smith JP, MacFadyen J, et al. Multivitamins in the prevention of cancer in men: the Physicians’ Health Study II randomized controlled trial. JAMA. 2012;308:1871-80.